S-(2-Aminoethyl)isothiourea dihydrobromide

Discontinued Product

Unfortunately S-(2-Aminoethyl)isothiourea dihydrobromide (Cat. No. 0893) has been withdrawn from sale for commercial reasons.
Cat.No. 0893 - S-(2-Aminoethyl)isothiourea dihydrobromide | CAS No. 56-10-0
Description: Selective iNOS inhibitor, acts arginine binding site

Biological Activity

Selective inhibitor of inducible (type II) NO synthase.

Technical Data

M. Wt 281.01
Storage Desiccate at -20°C
CAS Number 56-10-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 281.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.56 mL 17.79 mL 35.59 mL
5 mM 0.71 mL 3.56 mL 7.12 mL
10 mM 0.36 mL 1.78 mL 3.56 mL
50 mM 0.07 mL 0.36 mL 0.71 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999

Southan et al (1995) Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br.J.Pharmacol. 114 510 PMID: 7533622

Southan et al (1996) Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform. Br.J.Pharmacol. 117 619 PMID: 8646406

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Keywords: S-(2-Aminoethyl)isothiourea dihydrobromide, supplier, iNOS, iNOS, Tocris Bioscience

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