Discontinued ProductUnfortunately S-(2-Aminoethyl)isothiourea dihydrobromide (Cat. No. 0893) has been withdrawn from sale for commercial reasons.
Selective inhibitor of inducible (type II) NO synthase.
|Storage||Desiccate at -20°C|
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 281.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.56 mL||17.79 mL||35.59 mL|
|5 mM||0.71 mL||3.56 mL||7.12 mL|
|10 mM||0.36 mL||1.78 mL||3.56 mL|
|50 mM||0.07 mL||0.36 mL||0.71 mL|
References are publications that support the products' biological activity.
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999
Southan et al (1995) Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br.J.Pharmacol. 114 510 PMID: 7533622
Southan et al (1996) Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform. Br.J.Pharmacol. 117 619 PMID: 8646406
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Keywords: S-(2-Aminoethyl)isothiourea dihydrobromide, supplier, iNOS, iNOS, Tocris Bioscience
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