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Submit ReviewS-(2-Aminoethyl)isothiourea dihydrobromide
Description: Selective iNOS inhibitor, acts arginine binding site
Biological Activity
Selective inhibitor of inducible (type II) NO synthase.
Technical Data
| M. Wt | 281.01 |
| Storage | Desiccate at -20°C |
| CAS Number | 56-10-0 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
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References
References are publications that support the biological activity of the product.
Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204 PMID: 9226999
Southan et al (1995) Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br.J.Pharmacol. 114 510 PMID: 7533622
Southan et al (1996) Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform. Br.J.Pharmacol. 117 619 PMID: 8646406
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Keywords: S-(2-Aminoethyl)isothiourea dihydrobromide, S-(2-Aminoethyl)isothiourea dihydrobromide supplier, iNOS, 0893, Tocris Bioscience
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