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Discontinued ProductRupintrivir (Cat. No. 6414) has been withdrawn from sale for commercial reasons.
Biological Activity for Rupintrivir
Rupintrivir is a potent and selective irreversible human rhinovirus (HRV) 3C protease inhibitor (EC50 = 5 nM). Exhibits no significant inhibition against a variety of serine and cysteine proteases. Inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays.
Tocris products are for biomedical research use only. They are not intended for human or veterinary use.
Sold for research purposes under agreement from Pfizer Inc.
Technical Data for Rupintrivir
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Rupintrivir
References are publications that support the biological activity of the product.
Patick et al (1999) In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob.Agents Chemother. 43 2444 PMID: 10508022
Dragovich et al (1999) Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J.Med.Chem. 42 1203 PMID: 10197964
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Keywords: Rupintrivir, Rupintrivir supplier, HRV, inhibits, inhibitors, Potent, selective, irreversible, human, rhinovirus, 3C, protease, and, 3CL, Proteases, Other, Antivirals, 6414, Tocris Bioscience
Citations for Rupintrivir
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Currently there are no citations for Rupintrivir.
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