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Biological Activity for (RS)-Atenolol
(RS)-Atenolol is a cardioselective β-adrenergic blocker. Antihypertensive, antianginal and antiarrhythmic.
S-enantiomer also available.
Technical Data for (RS)-Atenolol
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (RS)-Atenolol
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for (RS)-Atenolol
The following data is based on the product molecular weight 266.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||15.02 mL||75.09 mL||150.18 mL|
|1.25 mM||3 mL||15.02 mL||30.04 mL|
|2.5 mM||1.5 mL||7.51 mL||15.02 mL|
|12.5 mM||0.3 mL||1.5 mL||3 mL|
References for (RS)-Atenolol
References are publications that support the biological activity of the product.
Kahonen et al (1994) Enhancement of arterial relaxation by long-term ate. treatment in spontaneously hypertensive rats. Br.J.Pharmacol. 112 925 PMID: 7921622
Merck Index 12 892
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1 Citation for (RS)-Atenolol
Citations are publications that use Tocris products. Selected citations for (RS)-Atenolol include:
Sood et al (2010) Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest 120 1515 PMID: 20389021
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.