(RS)-Atenolol

Pricing Availability Delivery Time Qty
Cat.No. 0387 - (RS)-Atenolol | C14H22N2O3 | CAS No. 29122-68-7
Description: β1 antagonist
Chemical Name: (RS)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
Datasheet
Citations (1)
Literature

Biological Activity

Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic. S-enantiomer (Cat. No. 0393) also available.

Technical Data

M. Wt 266.34
Formula C14H22N2O3
Storage Store at RT
CAS Number 29122-68-7
PubChem ID 2249
InChI Key METKIMKYRPQLGS-UHFFFAOYSA-N
Smiles CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 25 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 266.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.75 mL 18.77 mL 37.55 mL
5 mM 0.75 mL 3.75 mL 7.51 mL
10 mM 0.38 mL 1.88 mL 3.75 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Kahonen et al (1994) Enhancement of arterial relaxation by long-term atenolol treatment in spontaneously hypertensive rats. Br.J.Pharmacol. 112 925 PMID: 7921622

Merck Index 12 892 PMID:


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View all Adrenergic β1 Receptor Antagonists

Keywords: β1-adrenoceptors α1-adrenoceptor beta1-adrenoceptors antagonists b-Adrenergic β1-Adrenergic beta1-Adrenergic Receptors b1-adrenoceptors Adrenergic Beta-1 Receptors

1 Citation for (RS)-Atenolol

Citations are publications that use Tocris products. Selected citations for (RS)-Atenolol include:

Sood et al (2010) Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest 120 1515 PMID: 20389021


Do you know of a great paper that uses (RS)-Atenolol from Tocris? If so please let us know.

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Literature in this Area

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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Pathways for (RS)-Atenolol

Protocols

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