Discontinued Product

(RS)-α-Methyl-3-carboxymethylphenylglycine (Cat. No. 0856) has been withdrawn from sale for commercial reasons.
Description: Non-selectivem Glu antagonist
Literature (3)

Biological Activity

Group I/group II mGlu antagonist at cloned receptors.

Technical Data

M. Wt 223.23
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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References are publications that support the biological activity of the product.

Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323 PMID: 8719814

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

Watkins and Collingridge (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 15 333 PMID: 7992387

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Keywords: (RS)-a-Methyl-3-carboxymethylphenylglycine, (RS)-a-Methyl-3-carboxymethylphenylglycine supplier, Non-selective, mGlu, 0856, Tocris Bioscience

Citations for (RS)-α-Methyl-3-carboxymethylphenylglycine

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Currently there are no citations for (RS)-α-Methyl-3-carboxymethylphenylglycine.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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Parkinson's Disease Poster

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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.