(RS)-α-Methyl-3-carboxymethylphenylglycine

Discontinued Product

(RS)-α-Methyl-3-carboxymethylphenylglycine (Cat. No. 0856) has been withdrawn from sale for commercial reasons.
Cat.No. 0856 - (RS)-a-Methyl-3-carboxymethylphenylglycine
Description: Non-selectivem Glu antagonist
Datasheet
Citations
Reviews
Literature

Biological Activity

Group I/group II mGlu antagonist at cloned receptors.

Technical Data

M. Wt 223.23
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References

References are publications that support the biological activity of the product.

Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323 PMID: 8719814

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

Watkins and Collingridge (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 15 333 PMID: 7992387

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Keywords: (RS)-a-Methyl-3-carboxymethylphenylglycine, (RS)-a-Methyl-3-carboxymethylphenylglycine supplier, Non-selective, mGlu, 0856, Tocris Bioscience

Citations for (RS)-α-Methyl-3-carboxymethylphenylglycine

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

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  • Frizzled Receptors
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Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

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  • G-Protein-Coupled Receptors
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Metabotropic Glutamate Receptors

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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Epilepsy Poster

Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.

Learning & Memory

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

Parkinson's

Parkinson's Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.