Rosmarinic acid

Discontinued Product

Rosmarinic acid (Cat. No. 0630) has been withdrawn from sale for commercial reasons.
Description: GPR35 agonist; anti-inflammatory, cytostatic and antiviral
Chemical Name: [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid
Purity: ≥99% (HPLC)

Biological Activity for Rosmarinic acid

Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.

Technical Data for Rosmarinic acid

M. Wt 360.32
Formula C18H16O8
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 20283-92-5
PubChem ID 5281792
Smiles O=C(/C=C/C2=CC(O)=C(O)C=C2)O[C@@H](C(O)=O)CC1=CC(O)=C(O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Rosmarinic acid

Certificate of Analysis / Product Datasheet
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References for Rosmarinic acid

References are publications that support the biological activity of the product.

Van Kessel et al (1986) Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes. Agents Actions. 17 375 PMID: 3962787

Bult et al (1985) Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. Br.J.Pharmacol. 84 317 PMID: 3838489

Rampart et al (1986) Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid. Biochem.Pharmacol. 35 1397 PMID: 3516156

Sahu et al (1999) Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b. Biochem.Pharmacol. 57 1439 PMID: 10353266

Deng et al (2012) Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2 373 PMID: 22523636

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Keywords: Rosmarinic acid, Rosmarinic acid supplier, Anti-inflammatory, cytostatic, antiviral, GPR35, agonists, agonism, Non-selective, Antivirals, 0630, Tocris Bioscience

Citations for Rosmarinic acid

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Currently there are no citations for Rosmarinic acid.

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