Rec 15/2615 dihydrochloride
Selective α1B-adrenoceptor antagonist (Ki values are 0.3, 1.9 and 2.6 nM at human α1B, α1A and α1D receptors respectively).
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 568.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.76 mL||8.8 mL||17.59 mL|
|5 mM||0.35 mL||1.76 mL||3.52 mL|
|10 mM||0.18 mL||0.88 mL||1.76 mL|
|50 mM||0.04 mL||0.18 mL||0.35 mL|
References are publications that support the products' biological activity.
Testa et al (1997) Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): Role of the alpha-1L adrenoceptor in tissue selectivity, part II. J.Pharmacol.Exp.Ther. 281 1284 PMID: 9190864
Bremner et al (2000) Ligand design for α1 adrenoceptor subtype selective antagonist. Bioorg.Med.Chem. 8 201 PMID: 10968279
Morston et al (2007) α1A-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br.J.Pharmacol. 150 112 PMID: 17115072
If you know of a relevant reference for Rec 15/2615 dihydrochloride, please let us know.
View Related Products by Product Action
Keywords: Rec 15/2615 dihydrochloride, supplier, Selective, α1B-adrenoceptor, alpha1B-adrenoceptor, a1b-adrenoceptor, antagonists, α1b-adrenergic, alpha1b-adrenergic, a1b-adrenergic, Receptors, Rec15/2615, dihydrochloride, Adrenergic, Alpha-1, Receptors, Adrenergic, Alpha-1, Receptors, Tocris Bioscience
Citations for Rec 15/2615 dihydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Rec 15/2615 dihydrochloride. Do you know of a great paper that uses Rec 15/2615 dihydrochloride from Tocris? If so please let us know.
Reviews for Rec 15/2615 dihydrochloride
There are currently no reviews for this product. Be the first to review Rec 15/2615 dihydrochloride and earn rewards!
Have you used Rec 15/2615 dihydrochloride?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.