(R)-(+)-m-Nitrobiphenyline oxalate

Discontinued Product

(R)-(+)-m-Nitrobiphenyline oxalate (Cat. No. 2948) has been withdrawn from sale for commercial reasons.
Description: Potent α2C agonist
Chemical Name: (R)-2-[1-(3'-Nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole oxalate
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity for (R)-(+)-m-Nitrobiphenyline oxalate

α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM). Behaves as an antagonist at α2A and α2B adrenoceptors (pKb values are 7.11 and 6.07 respectively).

Technical Data for (R)-(+)-m-Nitrobiphenyline oxalate

M. Wt 401.38
Formula C17H17N3O3.C2H2O4
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 945618-97-3
Smiles O=C(O)C(O)=O.[H][C@](C3=NCCN3)(C)OC1=CC=CC=C1C2=CC([N+]([O-])=O)=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (R)-(+)-m-Nitrobiphenyline oxalate

References for (R)-(+)-m-Nitrobiphenyline oxalate

References are publications that support the biological activity of the product.

Crassous et al (2007) α2-adrenoreceptor profile modulation. 3. 1 -(+)-m-Nitrobiphenyline, a new efficient α2C-subtype selective agonist. J.Med.Chem. 50 3964 PMID: 17630725

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Citations for (R)-(+)-m-Nitrobiphenyline oxalate

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Currently there are no citations for (R)-(+)-m-Nitrobiphenyline oxalate.

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Literature in this Area

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