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Submit Review(R)-(+)-m-Nitrobiphenyline oxalate
Discontinued Product
(R)-(+)-m-Nitrobiphenyline oxalate (Cat. No. 2948) has been withdrawn from sale for commercial reasons.
Description: Potent α2C agonist
Chemical Name: (R)-2-[1-(3'-Nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole oxalate
Purity: ≥99% (HPLC)
Biological Activity for (R)-(+)-m-Nitrobiphenyline oxalate
α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM). Behaves as an antagonist at α2A and α2B adrenoceptors (pKb values are 7.11 and 6.07 respectively).
Technical Data for (R)-(+)-m-Nitrobiphenyline oxalate
| M. Wt | 401.38 |
| Formula | C17H17N3O3.C2H2O4 |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 945618-97-3 |
| Smiles | O=C(O)C(O)=O.[H][C@](C3=NCCN3)(C)OC1=CC=CC=C1C2=CC([N+]([O-])=O)=CC=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (R)-(+)-m-Nitrobiphenyline oxalate
References for (R)-(+)-m-Nitrobiphenyline oxalate
References are publications that support the biological activity of the product.
Crassous et al (2007) α2-adrenoreceptor profile modulation. 3. 1 -(+)-m-Nitrobiphenyline, a new efficient α2C-subtype selective agonist. J.Med.Chem. 50 3964 PMID: 17630725
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Keywords: (R)-(+)-m-Nitrobiphenyline oxalate, (R)-(+)-m-Nitrobiphenyline oxalate supplier, Potent, α2C-adrenoceptor, alpha2C-adrenoceptors, a2c-adrenoceptors, a2c-adrenergic, α2c-adrenergic, alpha2c-adrenergic, agonists, Receptors, Adrenergic, Alpha-2, 2948, Tocris Bioscience
Citations for (R)-(+)-m-Nitrobiphenyline oxalate
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Currently there are no citations for (R)-(+)-m-Nitrobiphenyline oxalate.
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