(R)-(+)-m-Nitrobiphenyline oxalate

Discontinued Product

(R)-(+)-m-Nitrobiphenyline oxalate (Cat. No. 2948) has been withdrawn from sale for commercial reasons.
Description: Potent α2C agonist
Chemical Name: (R)-2-[1-(3'-Nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole oxalate
Purity: ≥99% (HPLC)
Literature (2)

Biological Activity for (R)-(+)-m-Nitrobiphenyline oxalate

α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM). Behaves as an antagonist at α2A and α2B adrenoceptors (pKb values are 7.11 and 6.07 respectively).

Technical Data for (R)-(+)-m-Nitrobiphenyline oxalate

M. Wt 401.38
Formula C17H17N3O3.C2H2O4
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 945618-97-3
Smiles O=C(O)C(O)=O.[H][C@](C3=NCCN3)(C)OC1=CC=CC=C1C2=CC([N+]([O-])=O)=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (R)-(+)-m-Nitrobiphenyline oxalate

References for (R)-(+)-m-Nitrobiphenyline oxalate

References are publications that support the biological activity of the product.

Crassous et al (2007) α2-adrenoreceptor profile modulation. 3. 1 -(+)-m-Nitrobiphenyline, a new efficient α2C-subtype selective agonist. J.Med.Chem. 50 3964 PMID: 17630725

View Related Products by Target

View Related Products by Product Action

View all Adrenergic α2 Receptor Agonists

Keywords: (R)-(+)-m-Nitrobiphenyline oxalate, (R)-(+)-m-Nitrobiphenyline oxalate supplier, Potent, α2C-adrenoceptor, alpha2C-adrenoceptors, a2c-adrenoceptors, a2c-adrenergic, α2c-adrenergic, alpha2c-adrenergic, agonists, Receptors, Adrenergic, Alpha-2, 2948, Tocris Bioscience

Citations for (R)-(+)-m-Nitrobiphenyline oxalate

Citations are publications that use Tocris products.

Currently there are no citations for (R)-(+)-m-Nitrobiphenyline oxalate.

Reviews for (R)-(+)-m-Nitrobiphenyline oxalate

There are currently no reviews for this product. Be the first to review (R)-(+)-m-Nitrobiphenyline oxalate and earn rewards!

Have you used (R)-(+)-m-Nitrobiphenyline oxalate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.