PSN 375963 hydrochloride
GPR119 receptor agonist (EC50 values are 8.4 and 7.9 μM at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA) (Cat. No. 1484).
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 321.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.11 mL||15.54 mL||31.07 mL|
|5 mM||0.62 mL||3.11 mL||6.21 mL|
|10 mM||0.31 mL||1.55 mL||3.11 mL|
|50 mM||0.06 mL||0.31 mL||0.62 mL|
References are publications that support the products' biological activity.
Overton et al (2006) Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 3 167 PMID: 16517404
Ning et al (2008) Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br.J.Pharmacol. 155 1056 PMID: 18724386
If you know of a relevant reference for PSN 375963 hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: PSN 375963 hydrochloride, supplier, GPR119, receptors, agonists, PSN375963, hydrochloride, GPR119, GPR119, Tocris Bioscience
Citations for PSN 375963 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for PSN 375963 hydrochloride. Do you know of a great paper that uses PSN 375963 hydrochloride from Tocris? If so please let us know.
Reviews for PSN 375963 hydrochloride
There are currently no reviews for this product. Be the first to review PSN 375963 hydrochloride and earn rewards!
Have you used PSN 375963 hydrochloride?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review