PKC fragment (530-558)

Discontinued Product

PKC fragment (530-558) (Cat. No. 1887) has been withdrawn from sale for commercial reasons.
Cat.No. 1887 - PKC Fragment (530-558) | Leu-Leu-Tyr-Glu-Met-Leu-Ala-Gly-Gln-Ala-Pro-Phe-Glu-Gly-Glu-Asp-Glu-Asp-Glu-Leu-Phe-Gln-Ser-Ile-Met-Glu-His-Asn-Val-NH2 | CAS No. 122613-29-0
Description: Potent activator of protein kinase C
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent activator of protein kinase C (Ka ~ 10 mM); corresponds to residues 530-558 of the catalytic domain of PKC.

Technical Data

M. Wt 3354.7
Formula C148H221N35O50S2
Sequence LLYEMLAGQAPFEGEDEDELFQSIMEHNV

(Modifications: Val-29 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 122613-29-0
Smiles [H]N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

House et al (1989) A synthetic peptide analog of the putative substrate-binding motif activates protein kinase C. FEBS Lett. 249 243 PMID: 2737283

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Keywords: PKC Fragment (530-558), PKC Fragment (530-558) supplier, Potent, activators, protein, kinases, C, PKC, Protein, Kinase, Enzyme, Substrates, /, Activators, 1887, Tocris Bioscience

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