K+ channel opener and vasodilator. Activates KATP channels (IC50 for relaxation of coronary arteries = 1.26 μM). Clinically used antihypertensive agent.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
References are publications that support the biological activity of the product.
Gollasch et al (1995) Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J.Pharmacol.Exp.Ther. 275 681 PMID: 7473155
Kimura et al (1988) Effects of an antihypertensive vasodilator, pinacidil, on regional blood flow in conscious spontaneously hypertensive rats. J.Pharmacobiodyn. 11 430 PMID: 3171884
Petersen (1978) Synthesis and hypotensive activity of N-alkyl-N"-cyano-N'-pyridylguanidines. J.Med.Chem. 21 773 PMID: 691003
View Related Products by Product Action
Keywords: Pinacidil, Pinacidil supplier, Inward, rectifier, Potassium, Channels, 1503, Tocris Bioscience
Citations for Pinacidil
Citations are publications that use Tocris products.
Currently there are no citations for Pinacidil.
Reviews for Pinacidil
There are currently no reviews for this product. Be the first to review Pinacidil and earn rewards!
Have you used Pinacidil?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.