Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
(Modifications: X-1 = Ac-Nle, X-3 = beta-Ala, X-4 = D-2-Nal, Lys-7 = C-terminal amide, Asp-2, Lys-7, Cyclized)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in 25% ethanol / water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1008.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.99 mL||4.96 mL||9.92 mL|
|5 mM||0.2 mL||0.99 mL||1.98 mL|
|10 mM||0.1 mL||0.5 mL||0.99 mL|
|50 mM||0.02 mL||0.1 mL||0.2 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Grieco et al (2007) Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides. 28 1191 PMID: 17482720
If you know of a relevant reference for PG 106, please let us know.
Keywords: PG106 MC3 melanocortin receptors antagonists Melanocortin (MC) Receptor Peptide
Citations for PG 106
Citations are publications that use Tocris products.
Currently there are no citations for PG 106. Do you know of a great paper that uses PG 106 from Tocris? If so please let us know.