pep4c

Pricing Availability Delivery Time Qty
Cat.No. 1596 - pep4c | Lys-Arg-Met-Lys-Val-Ala-Lys-Ser-Ala-Gln | CAS No. 243843-43-8
Description: Inactive control peptide for pep2m (Cat. No. 1595)
Alternative Names: GluR4cr
Datasheet
Citations
Literature

Biological Activity

Inactive control peptide analog of pep2m (Cat. No. 1595), a peptide inhibitor of the interaction between the C-terminus of the GluR2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).

Technical Data

M. Wt 1146.42
Formula C48H91N17O13S
Sequence KRMKVAKSAQ
Storage Desiccate at -20°C
CAS Number 243843-43-8
PubChem ID 90471151
InChI Key PUDVEKDEUNWDBZ-SKYKFSGJSA-N
Smiles [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1146.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.87 mL 4.36 mL 8.72 mL
5 mM 0.17 mL 0.87 mL 1.74 mL
10 mM 0.09 mL 0.44 mL 0.87 mL
50 mM 0.02 mL 0.09 mL 0.17 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Collingridge and Isaac (2003) Functional roles of protein interactions with AMPA and kainate receptors. Neurosci.Res. 47 3 PMID: 12941441

Luscher et al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649 PMID: 10595516

Luthi et al (1999) Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron 24 389 PMID: 10571232

Nishimune et al (1998) NSF binding to GluR2 regulates synaptic transmission. Neuron 21 87 PMID: 9697854

Noel et al (1999) Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron 23 365 PMID: 10399941


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Keywords: pep4c, supplier, Inactive, control, peptide, 1595, Glutamate, AMPA, Receptors, iGlu, Ionotropic, GluR4cr, AMPA, Receptors, AMPA, Receptors, Tocris Bioscience

Citations for pep4c

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