Inactive control peptide analog of pep2-SVKI, an inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit.
Active Analog also available.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in 67% acetic acid|
Preparing Stock Solutions
The following data is based on the product molecular weight 1300.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.77 mL||3.84 mL||7.69 mL|
|5 mM||0.15 mL||0.77 mL||1.54 mL|
|10 mM||0.08 mL||0.38 mL||0.77 mL|
|50 mM||0.02 mL||0.08 mL||0.15 mL|
References are publications that support the products' biological activity.
Collingridge and Isaac (2003) Functional roles of protein interactions with AMPA and kainate receptors. Neurosci.Res. 47 3 PMID: 12941441
Daw et al (2000) PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron 28 873 PMID: 11163273
Kim et al (2001) Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc.Natl.Acad.Sci.U.S.A. 98 11725 PMID: 11573007
Li et al (1999) AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses. Nat.Neurosci. 2 972 PMID: 10526335
If you know of a relevant reference for pep2-SVKE, please let us know.
Keywords: pep2-SVKE, supplier, Inactive, control, peptide, 1597, Glutamate, AMPA, Receptors, iGlur, Ionotropic, AMPA, Receptors, AMPA, Receptors, Tocris Bioscience
1 Citation for pep2-SVKE
Citations are publications that use Tocris products. Selected citations for pep2-SVKE include:
Dickinson et al (2009) A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha. Mol Brain 2 18 PMID: 19534762
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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