Pep1-TGL
Biological Activity
Peptide containing the 'TGL' motif that corresponds to the C-terminus of the AMPA receptor GluR1 subunit.
Analog also available.
Technical Data
| M. Wt | 990.14 |
| Formula | C41H71N11O15S |
| Sequence | SSGMPLGATGL |
| Storage | Desiccate at -20°C |
| PubChem ID | 90479811 |
| InChI Key | YITYOVFAFHLILZ-BRZHPJNDSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 2 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 990.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.01 mL | 5.05 mL | 10.1 mL |
| 5 mM | 0.2 mL | 1.01 mL | 2.02 mL |
| 10 mM | 0.1 mL | 0.5 mL | 1.01 mL |
| 50 mM | 0.02 mL | 0.1 mL | 0.2 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Hayashi et al (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287 2262 PMID: 10731148
Shi et al (2001) Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell 105 331 PMID: 11348590
If you know of a relevant reference for Pep1-TGL, please let us know.
View Related Products by Target
Keywords: Pep1-TGL, supplier, GluR1, subunit, C-terminus, peptide, Glutamate, AMPA, Receptors, iGluR, Ionotropic, AMPA, Receptors, AMPA, Receptors, Tocris Bioscience
2 Citations for Pep1-TGL
Citations are publications that use Tocris products. Selected citations for Pep1-TGL include:
McElligott et al (2010) Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. J Neuroimmunol 107 2271 PMID: 20133871
Cho et al (2012) Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit. J Neurosci 32 14165 PMID: 23055486
Do you know of a great paper that uses Pep1-TGL from Tocris? If so please let us know.
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