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Submit ReviewPep1-TGL
Description: GluA1 subunit C-terminus peptide analog
Biological Activity
Peptide containing the 'TGL' motif that corresponds to the C-terminus of the AMPA receptor GluA1 subunit.
Analog also available.
Technical Data
| M. Wt | 990.14 |
| Formula | C41H71N11O15S |
| Sequence | SSGMPLGATGL |
| Storage | Desiccate at -20°C |
| PubChem ID | 90479811 |
| InChI Key | YITYOVFAFHLILZ-BRZHPJNDSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solubility | Soluble to 2 mg/ml in water |
Product Datasheets
References
References are publications that support the biological activity of the product.
Hayashi et al (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287 2262 PMID: 10731148
Shi et al (2001) Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell 105 331 PMID: 11348590
If you know of a relevant reference for Pep1-TGL, please let us know.
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Keywords: Pep1-TGL, Pep1-TGL supplier, GluR1, subunit, C-terminus, peptide, Glutamate, AMPA, Receptors, iGluR, Ionotropic, GluA1, 1601, Tocris Bioscience
4 Citations for Pep1-TGL
Citations are publications that use Tocris products. Selected citations for Pep1-TGL include:
McElligott et al (2010) Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. J Neuroimmunol 107 2271 PMID: 20133871
Cho et al (2012) Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit. J Neurosci 32 14165 PMID: 23055486
Tazerart et al (2020) A spike-timing-dependent plasticity rule for dendritic spines Nat Commun 11 4276 PMID: 32848151
Glasgow et al (2018) Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus. Cell Rep 25 168 PMID: 30282026
Do you know of a great paper that uses Pep1-TGL from Tocris? Please let us know.
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