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FAAH activator; proposed to enhance amidohydrolase activity of FAAH by reducing negative feedback mechanisms.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 405.61. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.93 mL||24.65 mL||49.31 mL|
|2.5 mM||0.99 mL||4.93 mL||9.86 mL|
|5 mM||0.49 mL||2.47 mL||4.93 mL|
|25 mM||0.1 mL||0.49 mL||0.99 mL|
References are publications that support the biological activity of the product.
Faure et al (2014) Synthesis of phenoxyacyl-ethanolamides and their effects on fatty acid amide hydrolase activity. J.Biol.Chem. 289 9340 PMID: 24558037
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Keywords: PDP-EA, PDP-EA supplier, FAAH, activators, enhances, amidohydrolase, activity, fatty, acid, amide, hydrolase, Fatty, Acid, Amide, Hydrolase, (FAAH), Other, Cannabinoids, 5210, Tocris Bioscience
1 Citation for PDP-EA
Citations are publications that use Tocris products. Selected citations for PDP-EA include:
Song et al (2018) Selective Role of RGS9-2 in Regulating Retrograde Synaptic Signaling of Indirect Pathway Medium Spiny Neurons in Dorsal Striatum. J Neurosci 38 7120 PMID: 30006367
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.