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Cat.No. 4161 - Paricalcitol | C27H44O3 | CAS No. 131918-61-1
Description: Analog of the active form of vitamin D2
Chemical Name: (1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Purity: ≥98% (HPLC)
Literature (2)

Biological Activity for Paricalcitol

Paricalcitol is an analog of the active form of vitamin D2; activates the vitamin D receptor.

Technical Data for Paricalcitol

M. Wt 416.64
Formula C27H44O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 131918-61-1
PubChem ID 5281104
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](/C=C/[C@H](C)C(C)(O)C)C)([H])/C2=C/C=C1C[C@@H](O)C[C@H](O)C/1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Paricalcitol

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 2.08 5

Preparing Stock Solutions for Paricalcitol

The following data is based on the product molecular weight 416.64. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 48 mL 240.02 mL 480.03 mL
0.25 mM 9.6 mL 48 mL 96.01 mL
0.5 mM 4.8 mL 24 mL 48 mL
2.5 mM 0.96 mL 4.8 mL 9.6 mL

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Product Datasheets for Paricalcitol

Certificate of Analysis / Product Datasheet
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References for Paricalcitol

References are publications that support the biological activity of the product.

Suarez-Martinez et al (2014) Adiponectin expression and the cardioprotective role of the vitamin D receptor activator parical. and the angiotensin converting enzyme inhibitor enal. in ApoE-deficient mice. Ther.Adv.Cardiovasc.Dis 8 224 PMID: 25037058

Halder et al (2014) Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. Reprod Sci. 21 1108 PMID: 24925855

If you know of a relevant reference for Paricalcitol, please let us know.

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