Paricalcitol

Pricing Availability Delivery Time Qty
Cat.No. 4161 - Paricalcitol | C27H44O3 | CAS No. 131918-61-1
Description: Analog of the active form of vitamin D2
Chemical Name: (1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Analog of the active form of vitamin D2; activates the vitamin D receptor.

Technical Data

M. Wt 416.64
Formula C27H44O3
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 131918-61-1
PubChem ID 5281104
InChI Key BPKAHTKRCLCHEA-UBFJEZKGSA-N
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](/C=C/[C@H](C)C(C)(O)C)C)([H])/C2=C/C=C1C[C@@H](O)C[C@H](O)C/1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.08 5

Preparing Stock Solutions

The following data is based on the product molecular weight 416.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.4 mL 12 mL 24 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
10 mM 0.24 mL 1.2 mL 2.4 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Suarez-Martinez et al (2014) Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice. Ther.Adv.Cardiovasc.Dis 8 224 PMID: 25037058

Halder et al (2014) Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. Reprod Sci. 21 1108 PMID: 24925855


If you know of a relevant reference for Paricalcitol, please let us know.

View Related Products by Target

Keywords: Analog vitamin D2 active form Vitamin D Receptors

Citations for Paricalcitol

Citations are publications that use Tocris products.

Currently there are no citations for Paricalcitol. Do you know of a great paper that uses Paricalcitol from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
  • Retinoic Acid Receptors
  • Retinoid X Receptors
  • Vitamin D Receptors

Pathways for Paricalcitol

Protocols

TODO: Add Protocols