Pam3CSK4 Biotin

Discontinued Product

Pam3CSK4 Biotin (Cat. No. 4636) has been withdrawn from sale for commercial reasons.
Cat.No. 4636 - Pam3CSK4 Biotin | Pam3-Cys-Ser-Lys-Lys-Lys-Lys-Aca-Aca-Biotin
Description: Biotinylated Pam3CSK4 (Cat. No. 4633)
Datasheet
Citations
Reviews
Literature
Pathways

Biological Activity

Biotinylated Pam3CSK4 (Cat. No. 4633), a Toll-like receptor 1/2 agonist.

Technical Data

M. Wt 1962.85
Formula C103H192N14O17S2
Sequence CSKKKK

(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl]-Cys

, K6= aminocaproic acid-amonocaproic acid-biotin

Storage Store at -20°C
PubChem ID 90488959
InChI Key GVXJPWKMFMNHRE-XHHKIZCASA-N
Smiles [H]N([C@@H](CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H])C(O)=O)C(=O)CCCCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Marre et al (2010) Human integrin α3β1 regulates TLR2 recognition of lipopeptides from endosomal compartments. PLoS One 5 e12871 PMID: 20877569

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Keywords: Pam3CSK4 Biotin, Pam3CSK4 Biotin supplier, Pam3CSK4, Biotin, Toll-like, receptors, TLR1/2, agonists, Receptors, 4636, Tocris Bioscience

Citations for Pam3CSK4 Biotin

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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Pathways for Pam3CSK4 Biotin

Toll-like Receptor

Toll-like Receptor Signaling Pathway

TLR signaling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.