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Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A (Cat. No. 1455).
(Modifications: Leu-33 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Darker et al (2001) Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. Bioorg.Med.Chem.Lett. 11 737 PMID: 11266181
German et al (2013) Truncated orexin peptides: structure-activity relationship studies. Med.Chem.Lett. 4 1224 PMID: 24707347
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Keywords: OXA (17-33), OXA (17-33) supplier, Potent, selective, orexin, OX1, receptors, agonists, Receptor, 5115, Tocris Bioscience
1 Citation for OXA (17-33)
Citations are publications that use Tocris products. Selected citations for OXA (17-33) include:
Feng et al (2012) Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain. Drug Des Devel Ther 12 225 PMID: 23173601
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.