Pricing Availability   Qty
Cat.No. 1797 - OMDM-2 | C27H45NO3 | CAS No. 616884-63-0
Description: Potent inhibitor of anandamide uptake
Chemical Name: (9Z)-N-[1-((R)-4-Hydroxbenzyl)-2-hydroxyethyl]-9-octadecenamide
Purity: ≥99% (HPLC)
Citations (1)
Literature (3)

Biological Activity

Metabolically stable inhibitor of anandamide cellular uptake (Ki = 3 μM). Displays relatively low affinity for CB1 and CB2 receptors (Ki values are 5.1 and > 10 μM) and for vanilloid VR1 receptors (EC50 = 10 μM). FABP inhibitor. Has minimal activity against FAAH (Ki > 50 μM). Active in vivo.

Technical Data

M. Wt 431.66
Formula C27H45NO3
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 616884-63-0
PubChem ID 9928181

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 4.32 10
DMSO 4.32 10

Preparing Stock Solutions

The following data is based on the product molecular weight 431.66. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.17 mL 115.83 mL 231.66 mL
0.5 mM 4.63 mL 23.17 mL 46.33 mL
1 mM 2.32 mL 11.58 mL 23.17 mL
5 mM 0.46 mL 2.32 mL 4.63 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.


References are publications that support the biological activity of the product.

Ortar et al (2003) Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem.Pharmacol. 35 1473 PMID: 12732359

de Lago et al (2004) In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. Eur.J.Pharmacol. 484 249 PMID: 14744610

Deutsch (2016) A personal retrospective: Elevating Anandamide (AEA) by targeting fatty acid amide hydrolase (FAAH) and the fatty acid binding proteins (FABPs). Front.Pharmacol. 7 370 PMID: 27790143

If you know of a relevant reference for OMDM-2, please let us know.

View Related Products by Product Action

View all Cannabinoid Transporter Inhibitors

Keywords: OMDM-2, OMDM-2 supplier, Potent, inhibitors, inhibits, anandamide, reuptake, AMT, Transporters, cannabinoids, Monoamine, Neurotransmitter, FABPs, FABP, fatty, acid, binding, proteins, Cannabinoid, Fatty, Acid, Binding, Proteins, 1797, Tocris Bioscience

1 Citation for OMDM-2

Citations are publications that use Tocris products. Selected citations for OMDM-2 include:

Bátkai et al (2004) Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. FASEB J 110 1996 PMID: 15451779

Do you know of a great paper that uses OMDM-2 from Tocris? Please let us know.

Reviews for OMDM-2

There are currently no reviews for this product. Be the first to review OMDM-2 and earn rewards!

Have you used OMDM-2?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Cannabinoid Receptor Ligands

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.


Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.