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Submit ReviewObestatin (human)
Description: Endogenous reported anorexigenic peptide
Biological Activity for Obestatin (human)
Obestatin (human) is an endogenous peptide derived from the same prepropeptide as ghrelin. Reported to suppress food intake and reduce body weight-gain in rats.
Technical Data for Obestatin (human)
| M. Wt | 2546.86 |
| Formula | C116H176N32O33 |
| Sequence |
FNAPFDVGIKLSGVQYQQHSQAL (Modifications: Leu-23 = C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 1081110-72-6 |
| PubChem ID | 91826105 |
| InChI Key | IXQOGPZNKNSCJR-QQDMDDJXSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Obestatin (human)
References for Obestatin (human)
References are publications that support the biological activity of the product.
Tang et al (2008) Obestatin: its physicochemical characteristics and physiological functions. Peptides 29 639 PMID: 18325633
Zhang et al (2005) Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310 996 PMID: 16284174
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Keywords: Obestatin (human), Obestatin (human) supplier, Endogenous, anorexigenic, peptide, Peptide, Receptor, Receptors, GPR39, Other, Ghrelin, 5560, Tocris Bioscience
Citations for Obestatin (human)
Citations are publications that use Tocris products.
Currently there are no citations for Obestatin (human).
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.