Ghrelin (human)

Pricing Availability   Qty
Cat.No. 1463 - Ghrelin (human) | Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg | CAS No. 258279-04-8
Description: Endogenous ghrelin receptor agonist
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.

Licensing Information

This peptide is distributed under license from Dr. Kangawa

Technical Data

M. Wt 3370.9
Formula C149H249N47O42
Sequence GSSFLSPEHQRVQQRKESKKPPAKLQPR

(Modifications: Ser-3 = Ser(n-octanoyl))

Storage Desiccate at -20°C
CAS Number 258279-04-8
PubChem ID 16133832
InChI Key GNKDKYIHGQKHHM-RJKLHVOGSA-N
Smiles [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](COC(=O)CCCCCCC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 2 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Inui (2001) Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat.Rev.Neurosci. 2 551 PMID: 11483998

Kojima et al (1999) Ghrelin is growth-hormone-releasing acylated peptide from stomach. Nature 402 656 PMID: 10604470

Tolle et al (2001) In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology 73 54 PMID: 11174017


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Keywords: Ghrelin (human), Ghrelin (human) supplier, Endogenous, ghrelin, receptor, agonists, GHS-R1a, Receptors, Growth, Hormone, Secretagog, Receptor, 1a, peptides, acylated, Ghrelin, 1463, Tocris Bioscience

1 Citation for Ghrelin (human)

Citations are publications that use Tocris products. Selected citations for Ghrelin (human) include:

Rodríguez et al (2009) Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes. Sci Signal 33 541 PMID: 19238155


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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