Ghrelin (human)

Pricing Availability Delivery Time Qty
Cat.No. 1463 - Ghrelin (human) | Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg | CAS No. 258279-04-8
Description: Endogenous ghrelin receptor agonist
Datasheet
Citations (1)
Literature

Biological Activity

Endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.

Licensing Information

This peptide is distributed under license from Dr. Kangawa

Technical Data

M. Wt 3370.9
Formula C149H249N47O42
Sequence GSSFLSPEHQRVQQRKESKKPPAKLQPR

(Modifications: Ser-3 = Ser(n-octanoyl))

Storage Desiccate at -20°C
CAS Number 258279-04-8
PubChem ID 16133832
InChI Key GNKDKYIHGQKHHM-RJKLHVOGSA-N
Smiles [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](COC(=O)CCCCCCC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3370.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.3 mL 1.48 mL 2.97 mL
5 mM 0.06 mL 0.3 mL 0.59 mL
10 mM 0.03 mL 0.15 mL 0.3 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Inui (2001) Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat.Rev.Neurosci. 2 551 PMID: 11483998

Kojima et al (1999) Ghrelin is growth-hormone-releasing acylated peptide from stomach. Nature 402 656 PMID: 10604470

Tolle et al (2001) In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology 73 54 PMID: 11174017


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Keywords: Ghrelin (human), supplier, Endogenous, ghrelin, receptor, agonists, GHS-R1a, Receptors, Growth, Hormone, Secretagog, Receptor, 1a, peptides, acylated, Ghrelin, Receptors, Tocris Bioscience

1 Citation for Ghrelin (human)

Citations are publications that use Tocris products. Selected citations for Ghrelin (human) include:

Rodríguez et al (2009) Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes. Sci Signal 33 541 PMID: 19238155


Do you know of a great paper that uses Ghrelin (human) from Tocris? If so please let us know.

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