NU 1025

Discontinued Product

NU 1025 (Cat. No. 1401) has been withdrawn from sale for commercial reasons.
Description: Potent PARP inhibitor
Chemical Name: 8-Hydroxy-2-methyl-4(3H)-quinazolinone
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (4)

Biological Activity for NU 1025

NU 1025 is a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.

Technical Data for NU 1025

M. Wt 176.17
Formula C9H8N2O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 90417-38-2
PubChem ID 63306
InChI Key YJDAOHJWLUNFLX-UHFFFAOYSA-N
Smiles CC1=NC2=C(O)C=CC=C2C(=O)N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for NU 1025

Certificate of Analysis / Product Datasheet
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View all Poly(ADP-Ribose) Polymerase Inhibitors

Keywords: NU 1025, NU 1025 supplier, Potent, PARP, inhibitors, inhibits, PolyADP-ribose, Polymerases, NU1025, Poly(ADP-ribose), Polymerase, 1401, Tocris Bioscience

1 Citation for NU 1025

Citations are publications that use Tocris products. Selected citations for NU 1025 include:

Sultana et al (2012) Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors. Int J Cancer 131 2433 PMID: 22377908


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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