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NPS ALX Compound 4a dihydrochloride
Discontinued ProductNPS ALX Compound 4a dihydrochloride (Cat. No. 3285) has been withdrawn from sale for commercial reasons.
Biological Activity for NPS ALX Compound 4a dihydrochloride
NPS ALX Compound 4a dihydrochloride is a potent and competitive 5-HT6 antagonist (IC50 = 7.2 nM, Ki = 0.2 nM) that displays selectivity over other 5-HT and D2 receptors.
Technical Data for NPS ALX Compound 4a dihydrochloride
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for NPS ALX Compound 4a dihydrochloride
References for NPS ALX Compound 4a dihydrochloride
References are publications that support the biological activity of the product.
Isaac et al (2000) 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg.Med.Chem.Letts. 10 1719
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Keywords: NPS ALX Compound 4a dihydrochloride, NPS ALX Compound 4a dihydrochloride supplier, Potent, selective, 5-HT6, antagonists, Serotonin, Receptors, 5-Hydroxytryptamine, NPSALX, Compound4a, dihydrochloride, 3285, Tocris Bioscience
Citations for NPS ALX Compound 4a dihydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for NPS ALX Compound 4a dihydrochloride.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.