NPEC-caged-(S)-3,5-DHPG

Discontinued Product

NPEC-caged-(S)-3,5-DHPG (Cat. No. 2923) has been withdrawn from sale for commercial reasons.
Description: Caged (S)-3,5-DHPG (Cat. No. 0805)
Chemical Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-3,3-Dihydroxyphenylglycine
Purity: ≥97% (HPLC)
Datasheet
Citations
Reviews
Literature (6)

Biological Activity for NPEC-caged-(S)-3,5-DHPG

1-(2-nitrophenyl)ethyl caged version of (S)-3,5-DHPG (Cat. No. 0805).

Technical Data for NPEC-caged-(S)-3,5-DHPG

M. Wt 376.32
Formula C17H16N2O8
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 1257323-86-6
Smiles OC1=CC(O)=CC([C@@H](C(O)=O)NC(OC(C2=C([N+]([O-])=O)C=CC=C2)C)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for NPEC-caged-(S)-3,5-DHPG

References for NPEC-caged-(S)-3,5-DHPG

References are publications that support the biological activity of the product.

Palma-Cerda et al (2012) New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 63 624 PMID: 22609535

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Citations for NPEC-caged-(S)-3,5-DHPG

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Currently there are no citations for NPEC-caged-(S)-3,5-DHPG.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Huntington's Disease Poster

Huntington's Disease Poster

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

Learning & Memory Poster

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.