Noradrenaline bitartrate

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Cat.No. 5169 - Noradrenaline bitartrate | C8H11NO3.C4H6O6 | CAS No. 108341-18-0
Description: Endogenous adrenergic hormone and neurotransmitter
Alternative Names: Norepinephrine
Chemical Name: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol (L-(+))-bitartrate salt
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Endogenous adrenergic hormone and neurotransmitter. A classical stress hormone; underlies the fight or flight response, along with adrenaline. Increases heart rate. Vasoconstrictor.

Technical Data

M. Wt 319.26
Formula C8H11NO3.C4H6O6
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 108341-18-0
PubChem ID 25127519
InChI Key WNPNNLQNNJQYFA-YIDNRZKSSA-N
Smiles O[C@@H](CN)C1=CC(O)=C(O)C=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.93 100
water 31.93 100

Preparing Stock Solutions

The following data is based on the product molecular weight 319.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.13 mL 15.66 mL 31.32 mL
5 mM 0.63 mL 3.13 mL 6.26 mL
10 mM 0.31 mL 1.57 mL 3.13 mL
50 mM 0.06 mL 0.31 mL 0.63 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Bunney et al (1965) Norepinephrine in depressive reactions. A review. Arch.Gen.Psychiatry. 13 483 PMID: 5320621

Gary et al (1985) Stress and brain noradrenaline: A review. Neuroscience & Biobehavioral Reviews 9 233 PMID:

Lewitt et al (2012) Norepinephrine: the next therapeutics frontier for Parkinson's disease. Transl.Neurodegener. 1 4 PMID: 23211006


If you know of a relevant reference for Noradrenaline bitartrate, please let us know.

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Keywords: endogenous adrenergic hormones neurotransmitters vasoconstrictor stress Norepinephrine Non-selective Adrenergic Alpha Receptors

2 Citations for Noradrenaline bitartrate

Citations are publications that use Tocris products. Selected citations for Noradrenaline bitartrate include:

Baj et al (2012) Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology 37 1600 PMID: 22318196

Zemkova et al (2011) Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology 152 3842 PMID: 21828176


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Pathways for Noradrenaline bitartrate

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