Somatostatin sst4 receptor agonist that displays > 100-fold selectivity over sst2 receptors (Ki values are 6 and 621 nM for sst4 and sst2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC50 = 26 nM).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 556.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.8 mL||8.99 mL||17.97 mL|
|5 mM||0.36 mL||1.8 mL||3.59 mL|
|10 mM||0.18 mL||0.9 mL||1.8 mL|
|50 mM||0.04 mL||0.18 mL||0.36 mL|
References are publications that support the biological activity of the product.
Liu et al (1998) Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas. J.Med.Chem. 41 4693 PMID: 9822540
Liu et al (1999) 2-pyridylthioureas: novel nonpeptide somatostatin agonists with SST4 selectivity. Curr.Pharm.Des. 5 255 PMID: 10101224
If you know of a relevant reference for NNC 26-9100, please let us know.
View Related Products by Product Action
Keywords: NNC 26-9100, NNC 26-9100 supplier, Selective, sst4, agonists, Receptors, Somatostatin, NNC269100, 2440, Tocris Bioscience
1 Citation for NNC 26-9100
Citations are publications that use Tocris products. Selected citations for NNC 26-9100 include:
Honda et al (2012) Inhibitory effect of somatostatin receptor subtype-4 agonist NNC 26-9100 on micturition reflex in rats. Urology 80 1391000000000 PMID: 22951005
Do you know of a great paper that uses NNC 26-9100 from Tocris? Please let us know.
Reviews for NNC 26-9100
There are currently no reviews for this product. Be the first to review NNC 26-9100 and earn rewards!
Have you used NNC 26-9100?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.