Neuropeptide Y 13-36 (porcine)

Pricing Availability Delivery Time Qty
Cat.No. 1177 - Neuropeptide Y 13-36 (porcine) | Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 | CAS No. 113662-54-7
Description: NPY Y2 receptor agonist
Alternative Names: NPY 13-36 (porcine)
Datasheet
Citations
Literature

Biological Activity

Neuropeptide Y2 receptor agonist.

Technical Data

M. Wt 2983
Formula C135H209N41O36
Sequence PAEDLARYYSALRHYINLITRQRY

(Modifications: Tyr-24 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 113662-54-7
PubChem ID 16142386
InChI Key HEALDAASUSTTPJ-QGTLAHJGSA-N
Smiles [H]N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 0.80 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2983. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.34 mL 1.68 mL 3.35 mL
5 mM 0.07 mL 0.34 mL 0.67 mL
10 mM 0.03 mL 0.17 mL 0.34 mL
50 mM 0.01 mL 0.03 mL 0.07 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Aguirre et al (1990) Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci.Lett. 118 5 PMID: 2259468

Aguirre et al (1995) Increased vasopressor actions of intraventricular neuropeptide Y-(13-36) in spontaneously hypertensive versus normotensive Wistar-Kyoto rats. Possible relationship to increases in Y2 receptor binding in the nucleus tractus solitarius. Brain Res. 684 159 PMID: 7583217

Martire et al (1993) Region-specific inhibition of potassium-evoked [3H]noradrenaline release from rat brain synaptosomes by neuropeptide Y-(13-36). Involvement of NPY receptors of the Y2 type. Eur.J.Pharmacol. 230 231 PMID: 8422905


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Keywords: Y2 receptor agonists Neuropeptides Y Receptors NPY NeuropeptideY (porcine) 13-36 NPY1336 NPY 13-36 (porcine) NPY Receptors

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