Nalmefene - d3
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
Preparing Stock Solutions
The following data is based on the product molecular weight 342.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.92 mL||14.6 mL||29.2 mL|
|5 mM||0.58 mL||2.92 mL||5.84 mL|
|10 mM||0.29 mL||1.46 mL||2.92 mL|
|50 mM||0.06 mL||0.29 mL||0.58 mL|
References are publications that support the biological activity of the product.
Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678
Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980
Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022
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Keywords: Nalmefene - d3, Nalmefene - d3 supplier, opioid, receptors, antagonists, deuterated, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, 3971, Tocris Bioscience
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Literature in this Area
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Peptides Involved in Appetite Modulation Scientific Review
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
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