Nalmefene - d3

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Cat.No. 3971 - Nalmefene - d3 | C21H22D3NO3 | CAS No. 55096-26-9
Description: Deuterated nalmefene; opioid receptor antagonist
Chemical Name: (5α)-17-(d3-Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Deuterated nalmefene (Cat. No. 4085).

Technical Data

M. Wt 342.45
Formula C21H22D3NO3
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 55096-26-9
PubChem ID 71750904
InChI Key WJBLNOPPDWQMCH-TVFUAGGXSA-N
Smiles C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C([2H])([2H])C6([2H])CC6)CC4)[C@@](O)2CC3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in DMSO

Preparing Stock Solutions

The following data is based on the product molecular weight 342.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.92 mL 14.6 mL 29.2 mL
5 mM 0.58 mL 2.92 mL 5.84 mL
10 mM 0.29 mL 1.46 mL 2.92 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678

Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980

Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022


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Keywords: Nalmefene - d3, supplier, opioid, receptors, antagonists, deuterated, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, Miscellaneous/Non-selective, Opioids, Tocris Bioscience

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