Nalmefene - d3
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
References are publications that support the biological activity of the product.
Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678
Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980
Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022
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Keywords: Nalmefene - d3, Nalmefene - d3 supplier, opioid, receptors, antagonists, deuterated, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, 3971, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.