Nalmefene - d3

Discontinued Product

Nalmefene - d3 (Cat. No. 3971) has been withdrawn from sale for commercial reasons.
Cat.No. 3971 - Nalmefene - d3 | C21H22D3NO3
Description: Deuterated nalmefene; opioid receptor antagonist
Chemical Name: (5α)-17-(d3-Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
Purity: ≥98% (HPLC)
Literature (5)

Biological Activity

Deuterated nalmefene.

Nalmefene also available.

Technical Data

M. Wt 342.45
Formula C21H22D3NO3
Storage Store at +4°C
Purity ≥98% (HPLC)
PubChem ID 71750904
Smiles C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C([2H])([2H])C6([2H])CC6)CC4)[C@@](O)2CC3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

Michel et al (1985) Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find.Exp.Clin.Pharmacol. 7 175 PMID: 2991678

Wang et al (1998) Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J.Emerg.Med. 16 471 PMID: 9610980

Osborn et al (2010) In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci. 86 624 PMID: 20159022

View Related Products by Product Action

View all Miscellaneous Opioid Antagonists

Keywords: Nalmefene - d3, Nalmefene - d3 supplier, opioid, receptors, antagonists, deuterated, 55096-26-9, Miscellaneous/Non-selective, Opioids, Stable, Isotopically, Labeled, Compounds, 3971, Tocris Bioscience

Citations for Nalmefene - d3

Citations are publications that use Tocris products.

Currently there are no citations for Nalmefene - d3.

Reviews for Nalmefene - d3

There are currently no reviews for this product. Be the first to review Nalmefene - d3 and earn rewards!

Have you used Nalmefene - d3?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling

Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Peptides Involved in Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.


Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.


Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.