Discontinued ProductUnfortunately N-Carbomethoxycarbonyl-D-prolyl-D-phenylalaninebenzyl ester (Cat. No. 0445) has been withdrawn from sale for commercial reasons.
Blocks gp120 binding to CD4 glycoprotein, reverses inhibition by gp120 of CD4-Class II MHC binding, preserves CD4-dependent lymphokine production in the presence of gp120 and inhibits infection by HIV.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 438.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.28 mL||11.4 mL||22.81 mL|
|5 mM||0.46 mL||2.28 mL||4.56 mL|
|10 mM||0.23 mL||1.14 mL||2.28 mL|
|50 mM||0.05 mL||0.23 mL||0.46 mL|
References are publications that support the products' biological activity.
Finberg et al (1990) Prevention of HIV-I infection and preservation of CD4 function by the binding of CPS to gp 120. Science 249 287 PMID: 2115689
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Keywords: N-Carbomethoxycarbonyl-D-prolyl-D-phenylalaninebenzyl ester, supplier, Miscellaneous, Compounds, Miscellaneous, Compounds, Tocris Bioscience
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