Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewN-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide
Discontinued Product
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide (Cat. No. 0722) has been withdrawn from sale for commercial reasons.
Description: Nitroxyl precursor
Biological Activity
A pro-drug of the potent vasorelaxant nitroxyl, H-N=O, which it slowly releases in neutral solution. HNO eventually dimerizes and dehydrates to N2O, without producing NO. Also a powerful inhibitor of aldehyde dehydrogenase.
Technical Data
| M. Wt | 291.71 |
| Formula | C10H10ClNO5S |
| Storage | Desiccate at +4°C |
| CAS Number | 142867-52-5 |
| PubChem ID | 688598 |
| InChI Key | GWYBSWWLKXEDLB-UHFFFAOYSA-N |
| Smiles | ClC1=CC=C(S(N(C(C)=O)OC(C)=O)(=O)=O)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Fukuto et al (1992) N,O-Diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties. Biochem.Biophys.Res.Commun. 187 1367 PMID: 1417812
Lee et al (1992) Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase. J.Med.Chem. 35 3648 PMID: 1433175
View Related Products by Target
Keywords: N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide, N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide supplier, Nitroxyl, precursor, ROS, Donors, NO, Precursors, Nitric, Oxide, Signaling, Signalling, /, 0722, Tocris Bioscience
Citations for N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide
Citations are publications that use Tocris products.
Currently there are no citations for N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide.
Reviews for N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide
There are currently no reviews for this product. Be the first to review N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide and earn rewards!
Have you used N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Research Product Guide
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Angiogenesis
- Invasion and Metastasis