N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide

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Cat.No. 0763 - N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide | C14H19IN2O | CAS No. 155054-42-5
Description: σ1 selective ligand
Alternative Names: IPAB
Datasheet
Citations
Literature

Biological Activity

σ-1 selective ligand which binds with high affinity to human malignant melanoma cells A 2058.

Technical Data

M. Wt 358.22
Formula C14H19IN2O
Storage Desiccate at +4°C
CAS Number 155054-42-5
PubChem ID 127898
InChI Key WCMWVYQHPUQKHW-UHFFFAOYSA-N
Smiles IC1=CC=C(C=C1)C(=O)NCCN1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.82 100

Preparing Stock Solutions

The following data is based on the product molecular weight 358.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.79 mL 13.96 mL 27.92 mL
5 mM 0.56 mL 2.79 mL 5.58 mL
10 mM 0.28 mL 1.4 mL 2.79 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
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Safety Datasheet

References

References are publications that support the products' biological activity.

John et al (1994) [125I]N-(2-Piperidinylaminoethyl)-4-iodobenzamide and related analogues as sigma receptor imaging agents; high affinity binding to human malignant melanoma and rat C6 glioma cell lines. J.Labelled Comp.Radiopharm. 35 242 PMID:


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Keywords: σ1 sigma1 selective ligand Receptors IPAB Sigma1 Receptors

Citations for N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide

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