Sigma Receptors

Sigma receptors were initially thought to be the phencyclidine binding site on the NMDA receptor complex or a type of opioid receptor. They have since been distinguished from these two receptors and two subtypes of sigma receptors are now known; σ1 and σ2. σ1 and σ2 are distinguished by their stereoselectivity for pentazocine, SK&F 10047 and cyclazocine and have different tissue distribution patterns and subcellular localizations.

Literature (1)

Sigma Receptor Target Files

Related Targets

    Literature for Sigma Receptors

    Tocris offers the following scientific literature for Sigma Receptors to showcase our products. We invite you to request* your copy today!

    *Please note that Tocris will only send literature to established scientific business / institute addresses.

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    • Chemogenetics
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