Potent inhibitor of the Na+-dependent high-affinity synaptosomal glutamate transporter.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 171.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.84 mL||29.21 mL||58.43 mL|
|5 mM||1.17 mL||5.84 mL||11.69 mL|
|10 mM||0.58 mL||2.92 mL||5.84 mL|
|50 mM||0.12 mL||0.58 mL||1.17 mL|
References are publications that support the products' biological activity.
Bridges et al (1994) A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine carboxylate. Neurosci.Lett. 174 193 PMID: 7970177
If you know of a relevant reference for MPDC, please let us know.
View Related Products by Product Action
Keywords: MPDC, supplier, Potent, inhibitors, inhibits, L-glutamate, reuptake, EAAT, Excitatory, Amino, Acid, Transporters, GLAST, GLT-1, Glutamate, Monoamine, Neurotransmitter, Glutamate, Transporters, Glutamate, Transporters, Tocris Bioscience
Citations for MPDC
Citations are publications that use Tocris products.
Currently there are no citations for MPDC. Do you know of a great paper that uses MPDC from Tocris? If so please let us know.
Reviews for MPDC
There are currently no reviews for this product. Be the first to review MPDC and earn rewards!
Have you used MPDC?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Huntington's Disease Poster
Huntington's disease (HD) is a monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the MSN intracellular signaling pathways implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.