Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 535.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.87 mL||9.35 mL||18.69 mL|
|5 mM||0.37 mL||1.87 mL||3.74 mL|
|10 mM||0.19 mL||0.93 mL||1.87 mL|
|50 mM||0.04 mL||0.19 mL||0.37 mL|
References are publications that support the products' biological activity.
Edling et al (1995) Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. J.Pharmacol.Exp.Ther. 275 854 PMID: 7473177
Chrysant and Chrysant (2004) Pharmacological and clinical profile of moexipril: a concise review. J.Clin.Pharmacol. 44 827 PMID: 15286086
If you know of a relevant reference for Moexipril hydrochloride, please let us know.
View Related Products by Product Action
Keywords: Moexipril hydrochloride, supplier, Angiotensin-converting, enzyme, ACE, inhibitors, inhibits, Proteinases, Proteases, RS10085, RS, 10085, Angiotensin-Converting, Enzyme, Angiotensin-Converting, Enzyme, Tocris Bioscience
Citations for Moexipril hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Moexipril hydrochloride. Do you know of a great paper that uses Moexipril hydrochloride from Tocris? If so please let us know.
Reviews for Moexipril hydrochloride
There are currently no reviews for this product. Be the first to review Moexipril hydrochloride and earn rewards!
Have you used Moexipril hydrochloride?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review