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Discontinued ProductMoexipril hydrochloride (Cat. No. 2691) has been withdrawn from sale for commercial reasons.
Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Edling et al (1995) Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enal. J.Pharmacol.Exp.Ther. 275 854 PMID: 7473177
Chrysant and Chrysant (2004) Pharmacological and clinical profile of moexipril: a concise review. J.Clin.Pharmacol. 44 827 PMID: 15286086
Friehe and Ney (1997) Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moex. hydrochloride. Arzneim.-Forsch. 47 132
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Keywords: Moexipril hydrochloride, Moexipril hydrochloride supplier, Angiotensin-converting, enzyme, ACE, inhibitors, inhibits, Proteinases, Proteases, RS10085, RS, 10085, Angiotensin-Converting, Enzyme, 2691, Tocris Bioscience
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