Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor (IC50 = 144 nM). Displays selectively over LYPLA1 and 20 other serine hydrolases (IC50 values are >3000 and >10,000 nM respectively).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 454.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.2 mL||11 mL||22 mL|
|5 mM||0.44 mL||2.2 mL||4.4 mL|
|10 mM||0.22 mL||1.1 mL||2.2 mL|
|50 mM||0.04 mL||0.22 mL||0.44 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Adibekian et al (2010) Characterization of a selective, reversible inhibitor of lysophospholipase 2 (LYPLA2). Probe Reports from the NIH Molecular Libraries Program PMID: 24624468
If you know of a relevant reference for ML 349, please let us know.
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Keywords: ML 349, supplier, ML349, selective, reversible, Lysophospholipase, 2, LYPLA2, inhibitors, inhibits, serine, hydrolases, Other, Hydrolases, Other, Hydrolases, Tocris Bioscience
Citations for ML 349
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