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Submit ReviewMitoMark Red I
Description: Red fluorescent mitochondrial stain; cell permeable
Chemical Name: 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium chloride
Purity: ≥90% (HPLC)
Biological Activity for MitoMark Red I
MitoMark Red I is a red fluorescent mitochondrial stain. Fluorescence intensity is dependent on mitochondrial membrane potential. Excitation/emission maxima λ ~ 578/599 nm.
It is recommended to prepare stock solutions in DMSO.
Applications in HeLa cells for MitoMark Red I
Optical Data for MitoMark Red I
| Emission Color | Red |
|---|---|
| λabs | 578 nm |
| λem | 599 nm |
| Extinction Coefficient (ε) | 117000 M-1cm-1 |
Technical Data for MitoMark Red I
| M. Wt | 531.52 |
| Formula | C32H32Cl2N2O |
| Storage | Store at -20°C |
| Purity | ≥90% (HPLC) |
| CAS Number | 167095-09-2 |
| PubChem ID | 22613925 |
| InChI Key | IKEOZQLIVHGQLJ-UHFFFAOYSA-M |
| Smiles | ClCC(C=C1)=CC=C1C(C(C2=C3CCC4)=CC5=C3N4CCC5)=C6C(O2)=C7C8=[N+](CCC7)CCCC8=C6.[Cl-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MitoMark Red I
References for MitoMark Red I
References are publications that support the biological activity of the product.
Poot et al (1996) Analysis of mitochondrial morphology and function with novel fixable fluorescent stains. J.Histochem.Cytochem. 44 1363 PMID: 8985128
Buckman et al (2001) MitoTracker labeling in primary neuronal and astrocytic cultures: influence of mitochondrial membrane potential and oxidants. J.Neuroscience Methods. 104 165 PMID: 11164242
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Keywords: MitoMark Red I, MitoMark Red I supplier, mitomark, red, mitochondrial, marker, stain, mitotracker, mitochondria, Labels, and, Stains, Organelle, Cell, Structure, Other, Mitochondria, Dyes, Probes, 6445, Tocris Bioscience
Citations for MitoMark Red I
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Reviews for MitoMark Red I
Average Rating: 4 (Based on 1 Review.)
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Works fine.
By
Karthik Krishnamurthy on 08/03/2021
Assay Type: In Vitro
Species: Rat
Cell Line/Tissue: astrocytes
Labeled rat astrocytes with mitomark red at a concentration of 200 nM. Image captured using confocal microscope nikonA1R.
Be careful with laser intensity used to reduce bleaching.
Literature in this Area
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Fluorescent Dyes and Probes Research Product GuideUpdated
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals