Inactive control for (+)-JQ1 (Cat. No. 4499). Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the (+)-JQ1 probe summary on the SGC website.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 456.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.19 mL||10.94 mL||21.88 mL|
|5 mM||0.44 mL||2.19 mL||4.38 mL|
|10 mM||0.22 mL||1.09 mL||2.19 mL|
|50 mM||0.04 mL||0.22 mL||0.44 mL|
References are publications that support the products' biological activity.
Filippakopoulos et al (2010) Selective inhibition of BET bromodomains. Nature 468 1067 PMID: 20871596
If you know of a relevant reference for (-)-JQ1, please let us know.
Keywords: (-)-JQ1, supplier, inactive, analogs, negative, controls, bromodomains, BRD1, BRD2, BRD3, BRD4, Bromodomains, Bromodomains, Tocris Bioscience
1 Citation for (-)-JQ1
Citations are publications that use Tocris products. Selected citations for (-)-JQ1 include:
Perry et al (2015) BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle. Scientific Reports 290 9111 PMID: 25697361
Do you know of a great paper that uses (-)-JQ1 from Tocris? If so please let us know.
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