Meptazinol hydrochloride

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Cat.No. 3636 - Meptazinol hydrochloride | C15H23NO.HCl | CAS No. 59263-76-2
Description: μ1 partial agonist
Chemical Name: 3-(3-Ethylhexahydro-1-methyl-1H-azepin-3-yl)phenol hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Centrally active opioid analgesic. Partial agonist at the μ1 opioid receptor. Also shown to inhibit acetylcholinesterase.

Compound Libraries

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Technical Data

M. Wt 269.81
Formula C15H23NO.HCl
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 59263-76-2
PubChem ID 65483
InChI Key MPJUSISYVXABBH-UHFFFAOYSA-N
Smiles OC1=CC=CC(C2(CC)CN(C)CCCC2)=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.24 75
ethanol 26.98 100
water 26.98 100

Preparing Stock Solutions

The following data is based on the product molecular weight 269.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.71 mL 18.53 mL 37.06 mL
5 mM 0.74 mL 3.71 mL 7.41 mL
10 mM 0.37 mL 1.85 mL 3.71 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Spiegel and Pasternak (1984) Meptazinol: a novel Mu-1 selective opioid analgesic. J.Pharmacol.Exp.Ther. 228 414 PMID: 6141283

Galli et al (1996) Reversible inhibition of cholinesterases by opioids: possible pharmacological consequences. J.Pharm.Pharmacol. 48 116 PMID:


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Keywords: Meptazinol hydrochloride, supplier, Partial, agonists, μ1-opioid, mu1-opioid, Receptors, MOP, OP3, μ-opioid, mu-opioid, Mu, Opioid, Receptors, Mu, Opioid, Receptors, Tocris Bioscience

Citations for Meptazinol hydrochloride

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