MDL 29,913

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Cat.No. 1194 - MDL 29,913 | Cyclo[Gln-Trp-Phe-Gly-Leu-CH2N(CH3)-Leu] | CAS No. 135721-56-1
Description: Selective NK2 antagonist
Datasheet
Citations (1)
Reviews
Literature (6)

Biological Activity

NK2 tachykinin receptor selective antagonist.

Technical Data

M. Wt 745
Formula C40H56N8O6
Sequence QWFGLL

(Modifications: Leu-5 - Leu-6 = Leu-CH2N(CH3)-Leu, Cyclized)

Storage Desiccate at -20°C
CAS Number 135721-56-1
PubChem ID 90479769
InChI Key HTXNHRVBQSWFDI-QEQIFPIFSA-N
Smiles CC(C)C[C@@H]1NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.50 mg/ml in acetonitrile / water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Black et al (1992) Tachykinin receptors in rabbit airways - characterization by functional, autoradiographic and binding studies. Br.J.Pharmacol. 107 429 PMID: 1384914

Maggi et al (1993) MEN 10,573 and MEN 10,612, novel cyclic pseudopeptides which are potent tachykinin NK-2 receptor antagonists. Regul.Pept. 47 151 PMID: 8234901


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Keywords: MDL 29,913, MDL 29,913 supplier, Selective, NK2, antagonists, Tachykinin, Receptors, Neurokinin, MDL29913, Receptor, 1194, Tocris Bioscience

1 Citation for MDL 29,913

Citations are publications that use Tocris products. Selected citations for MDL 29,913 include:

Wease and Davies (2005) Substance P selectively decreases paired pulse depression in the rat hippocampal slice. BMC Neurosci 6 66 PMID: 16305744


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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