You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
(Modifications: Leu-6 = Leu(N-methyl), X = Nle & C-terminal amide)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Chassaing et al (1991) Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 19 91 PMID: 1658676
Matuszek et al (1998) An investigation of tachykinin NK2 receptor subtypes in the rat. Eur.J.Pharmacol. 352 103 PMID: 9718274
Burcher et al (2008) Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp.Ther. 324 170 PMID: 17959748
If you know of a relevant reference for [Lys5,MeLeu9,Nle10]-NKA(4-10), please let us know.
View Related Products by Product Action
Keywords: [Lys5,MeLeu9,Nle10]-NKA(4-10), [Lys5,MeLeu9,Nle10]-NKA(4-10) supplier, Selective, NK2, agonists, Tachykinin, Receptors, Neurokinin, Receptor, 3228, Tocris Bioscience
Citations for [Lys5,MeLeu9,Nle10]-NKA(4-10)
Citations are publications that use Tocris products.
Currently there are no citations for [Lys5,MeLeu9,Nle10]-NKA(4-10). Do you know of a great paper that uses [Lys5,MeLeu9,Nle10]-NKA(4-10) from Tocris? Please let us know.
Reviews for [Lys5,MeLeu9,Nle10]-NKA(4-10)
There are currently no reviews for this product. Be the first to review [Lys5,MeLeu9,Nle10]-NKA(4-10) and earn rewards!
Have you used [Lys5,MeLeu9,Nle10]-NKA(4-10)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.