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Immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T cells and inhibits angiogenesis in rats in vivo.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 308.33. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.24 mL||16.22 mL||32.43 mL|
|5 mM||0.65 mL||3.24 mL||6.49 mL|
|10 mM||0.32 mL||1.62 mL||3.24 mL|
|50 mM||0.06 mL||0.32 mL||0.65 mL|
References are publications that support the biological activity of the product.
Gonzalo et al (1994) Linomide inhibits programmed cell death of peripheral T cells in vivo. Eur.J.Immunol. 24 48 PMID: 8020570
Ichikawa et al (1992) The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers. Cancer Res. 52 3022 PMID: 1591718
Vukanovic et al (1993) Antiangiogenic effects of the quinoline-3-carboxamide linomide. Cancer Res. 53 1833 PMID: 7682157
If you know of a relevant reference for Linomide, please let us know.
Keywords: Linomide, Linomide supplier, Immunomodulators, antiangiogenics, Antiangiogenics, 1461, Tocris Bioscience
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Literature in this Area
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