Peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.
(Modifications: Arg-11 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in 20% acetonitrile / water|
References are publications that support the biological activity of the product.
Sanchez-Gomez et al (2008) Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 11 196 PMID: 19014450
Japelj et al (2005) Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 280 16955 PMID: 15687491
Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135 PMID: 15344905
If you know of a relevant reference for LF 11, please let us know.
Keywords: LF 11, LF 11 supplier, LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptide, antibiotics, Antibiotics, 4421, Tocris Bioscience
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