Lauryl-LF 11

Pricing Availability Delivery Time Qty
Cat.No. 4422 - Lauryl-LF 11 | CH3-(CH2)10-CO-NH-Phe-Gln-Trp-Gln-Arg-Asn-Ile-Arg-Lys-Val-Arg-NH2 | CAS No. 832729-14-3
Description: Analog of LF 11 (Cat. No. 4421); antibiotic
Datasheet
Citations
Reviews
Literature

Biological Activity

N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.

Technical Data

M. Wt 1712.11
Formula C81H134N26O15
Sequence FQWQRNIRKVR

(Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide)

Storage Store at -20°C
CAS Number 832729-14-3
PubChem ID 90488941
InChI Key AUHGQKBFMDAWAQ-BSHYLFJSSA-N
Smiles CCCCCCCCCCCNC(CC1CCCCC1)C(O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 2 mg/ml in 30% acetonitrile / water

Preparing Stock Solutions

The following data is based on the product molecular weight 1712.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.58 mL 2.92 mL 5.84 mL
5 mM 0.12 mL 0.58 mL 1.17 mL
10 mM 0.06 mL 0.29 mL 0.58 mL
50 mM 0.01 mL 0.06 mL 0.12 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Zweytick et al (2006) Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 1758 1426 PMID: 16616888

Rosenfeld et al (2010) Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 49 853 PMID: 20058937

Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135 PMID: 15344905


If you know of a relevant reference for Lauryl-LF 11, please let us know.

View Related Products by Target

Keywords: Lauryl-LF 11, Lauryl-LF 11 supplier, lauryl-LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptides, antibiotics, Antibiotics, 4422, Tocris Bioscience

Citations for Lauryl-LF 11

Citations are publications that use Tocris products.

Currently there are no citations for Lauryl-LF 11. Do you know of a great paper that uses Lauryl-LF 11 from Tocris? Please let us know.

Reviews for Lauryl-LF 11

There are currently no reviews for this product. Be the first to review Lauryl-LF 11 and earn rewards!

Have you used Lauryl-LF 11?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Aptamers
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells