Leelamine hydrochloride

Pricing Availability Delivery Time Qty
Cat.No. 2139 - Leelamine hydrochloride | C20H31N.HCl | CAS No. 16496-99-4
Description: CB1 agonist
Alternative Names: Lylamine hydrochloride, (+)-Dehydroabietylamine
Chemical Name: (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine hydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

CB1 agonist. Displaces binding of [3H]-SR141716A with an IC50 value of 2.86 μM.

Technical Data

M. Wt 321.93
Formula C20H31N.HCl
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 16496-99-4
PubChem ID 16759156
InChI Key CVPQLGCAWUAYPF-WFBUOHSLSA-N
Smiles NC[C@]1(C)CCC[C@@]3(C)[C@]([H])1CCC2=CC(C(C)C)=CC=C23.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.19 100
ethanol 32.19 100

Preparing Stock Solutions

The following data is based on the product molecular weight 321.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.11 mL 15.53 mL 31.06 mL
5 mM 0.62 mL 3.11 mL 6.21 mL
10 mM 0.31 mL 1.55 mL 3.11 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References

References are publications that support the products' biological activity.

If you know of a relevant reference for Leelamine hydrochloride, please let us know.

View Related Products by Target

View Related Products by Product Action

View all CB1 Receptor Agonists

Keywords: Leelamine hydrochloride, supplier, CB1, agonists, cannabinoids, Receptors, cb1r, Lylamine, hydrochloride, (+)-Dehydroabietylamine, CB1, Receptors, CB1, Receptors, Tocris Bioscience

Citations for Leelamine hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Leelamine hydrochloride. Do you know of a great paper that uses Leelamine hydrochloride from Tocris? If so please let us know.

Leelamine hydrochloride Reviews

Average Rating:

(Based on 0 Reviews)


1 Star
0%
2 Star
0%
3 Star
0%
4 Star
0%
5 Star
0%

Have you used Leelamine hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN Amazon gift card if you include an image -$10US/€7/£6/$10CAN Amazon gift card for reviews without an image. Limited to verified customers in USA, Canada and Europe.


Literature in this Area

GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Neurodegeneration

Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease
Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Cannabinoid Receptor Ligands

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.

Addiction

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Schizophrenia

Schizophrenia Poster

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.