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Submit ReviewL-Serine
Description: Weak endogenous glycine receptor agonist
Chemical Name: β-Hydroxyalanine
Purity: ≥99% (HPLC)
Biological Activity for L-Serine
L-Serine is an endogenous agonist at the inhibitory glycine receptor.
D-isomer also available.
Technical Data for L-Serine
| M. Wt | 105.09 |
| Formula | C3H7NO3 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 56-45-1 |
| PubChem ID | 5951 |
| InChI Key | MTCFGRXMJLQNBG-REOHCLBHSA-N |
| Smiles | OC[C@]([H])(N)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for L-Serine
References for L-Serine
References are publications that support the biological activity of the product.
Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607
Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923
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Keywords: L-Serine, L-Serine supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Amino, Acids, 0227, Tocris Bioscience
1 Citation for L-Serine
Citations are publications that use Tocris products. Selected citations for L-Serine include:
Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1 PMID: 20552041
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