L-Serine
Biological Activity
Endogenous agonist at the inhibitory glycine receptor. D-Serine (Cat. No. 0226) also available.
Technical Data
| M. Wt | 105.09 |
| Formula | C3H7NO3 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 56-45-1 |
| PubChem ID | 5951 |
| InChI Key | MTCFGRXMJLQNBG-REOHCLBHSA-N |
| Smiles | OC[C@]([H])(N)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 105.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 9.52 mL | 47.58 mL | 95.16 mL |
| 5 mM | 1.9 mL | 9.52 mL | 19.03 mL |
| 10 mM | 0.95 mL | 4.76 mL | 9.52 mL |
| 50 mM | 0.19 mL | 0.95 mL | 1.9 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607
Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923
If you know of a relevant reference for L-Serine, please let us know.
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Keywords: L-Serine, supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Glycine, Receptors, Tocris Bioscience
1 Citation for L-Serine
Citations are publications that use Tocris products. Selected citations for L-Serine include:
Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1 PMID: 20552041
Do you know of a great paper that uses L-Serine from Tocris? If so please let us know.
Literature in this Area
New Product Guide (Spring/Summer 2017)New
Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
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