L-Serine

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Cat.No. 0227 - L-Serine | C3H7NO3 | CAS No. 56-45-1
Description: Weak endogenous glycine receptor agonist
Chemical Name: β-Hydroxyalanine
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

Endogenous agonist at the inhibitory glycine receptor. D-Serine (Cat. No. 0226) also available.

Technical Data

M. Wt 105.09
Formula C3H7NO3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 56-45-1
PubChem ID 5951
InChI Key MTCFGRXMJLQNBG-REOHCLBHSA-N
Smiles OC[C@]([H])(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 105.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 9.52 mL 47.58 mL 95.16 mL
5 mM 1.9 mL 9.52 mL 19.03 mL
10 mM 0.95 mL 4.76 mL 9.52 mL
50 mM 0.19 mL 0.95 mL 1.9 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607

Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923


If you know of a relevant reference for L-Serine, please let us know.

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Keywords: L-Serine, supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Glycine, Receptors, Tocris Bioscience

1 Citation for L-Serine

Citations are publications that use Tocris products. Selected citations for L-Serine include:

Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1 PMID: 20552041


Do you know of a great paper that uses L-Serine from Tocris? If so please let us know.

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

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Pathways for L-Serine

Protocols

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