Discontinued Product

L-Serine (Cat. No. 0227) has been withdrawn from sale for commercial reasons.
Description: Weak endogenous glycine receptor agonist
Chemical Name: β-Hydroxyalanine
Purity: ≥99% (HPLC)
Citations (1)

Biological Activity for L-Serine

L-Serine is an endogenous agonist at the inhibitory glycine receptor.

D-isomer also available.

Technical Data for L-Serine

M. Wt 105.09
Formula C3H7NO3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 56-45-1
PubChem ID 5951
Smiles OC[C@]([H])(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for L-Serine

References are publications that support the biological activity of the product.

Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607

Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923

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Keywords: L-Serine, L-Serine supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Amino, Acids, 0227, Tocris Bioscience

1 Citation for L-Serine

Citations are publications that use Tocris products. Selected citations for L-Serine include:

Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1 PMID: 20552041

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