L-Serine

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Cat.No. 0227 - L-Serine | C3H7NO3 | CAS No. 56-45-1
Description: Weak endogenous glycine receptor agonist
Chemical Name: β-Hydroxyalanine
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Endogenous agonist at the inhibitory glycine receptor.

D-isomer also available.

Technical Data

M. Wt 105.09
Formula C3H7NO3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 56-45-1
PubChem ID 5951
InChI Key MTCFGRXMJLQNBG-REOHCLBHSA-N
Smiles OC[C@]([H])(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 100 mM in water

References

References are publications that support the biological activity of the product.

Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607

Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923


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Keywords: L-Serine, L-Serine supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Amino, Acids, 0227, Tocris Bioscience

1 Citation for L-Serine

Citations are publications that use Tocris products. Selected citations for L-Serine include:

Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1 PMID: 20552041


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Literature in this Area

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Ion Channel

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