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Submit ReviewPotent agonist, active at non-NMDA receptors. Excitotoxin, possibly involved in the aetiology of human lathyrism.
M. Wt | 198.11 |
Storage | Desiccate at RT |
CAS Number | 5302-45-4 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Baron et al (1990) Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site. Mol.Pharmacol. 38 554 PMID: 2172769
Bridges et al (1988) Inhibition of [3H]-AMPA binding by the excitotoxin β-N-oxalyl-L-α,β-diaminopropionic acid. Eur.J. Pharmacol. 145 357 PMID: 2895006
Ludolph et al (1987) Studies on the aetiology and pathogenesis of motor neurone diseases. Brain 110 149 PMID: 3801847
Spencer et al (1987) Guam amyotrophic lateral sclerosis - Parkinsonism - dementia linked to a plant excitant neurotoxin. Science 237 517 PMID: 3603037
Keywords: L-ODAP sodium salt, L-ODAP sodium salt supplier, L-BOAA, b-Oxalylamino-L-alanine, AMPA, Receptors, 0200, Tocris Bioscience
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