L-Kynurenine

Pricing Availability Delivery Time Qty
Cat.No. 4393 - L-Kynurenine | C10H12N2O3 | CAS No. 2922-83-0
Description: Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
Chemical Name: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Tryptophan catabolite; endogenous activator of the aryl hydrocarbon receptor (AhR). Immunosuppressant; suppresses allogeneic T cell proliferation.

Technical Data

M. Wt 208.21
Formula C10H12N2O3
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 2922-83-0
PubChem ID 161166
InChI Key YGPSJZOEDVAXAB-QMMMGPOBSA-N
Smiles O=C(C[C@H](N)C(O)=O)C1=C(N)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 10.41 50
DMSO 2.08 10
water 2.08 10

Preparing Stock Solutions

The following data is based on the product molecular weight 208.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.8 mL 24.01 mL 48.03 mL
5 mM 0.96 mL 4.8 mL 9.61 mL
10 mM 0.48 mL 2.4 mL 4.8 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Opitz et al (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478 197 PMID: 21976023


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View all Aryl Hydrocarbon Receptor Ligands

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Citations for L-Kynurenine

Citations are publications that use Tocris products.

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Literature in this Area

Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
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Pathways for L-Kynurenine

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