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L-Kynurenine is a tryptophan catabolite; endogenous activator of the aryl hydrocarbon receptor (AhR). Immunosuppressant; suppresses allogeneic T cell proliferation.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 208.21. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||48.03 mL||240.14 mL||480.28 mL|
|0.5 mM||9.61 mL||48.03 mL||96.06 mL|
|1 mM||4.8 mL||24.01 mL||48.03 mL|
|5 mM||0.96 mL||4.8 mL||9.61 mL|
References are publications that support the biological activity of the product.
Opitz et al (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478 197 PMID: 21976023
If you know of a relevant reference for L-Kynurenine, please let us know.
Keywords: L-Kynurenine, L-Kynurenine supplier, Kynurenine, tryptophan, catabolite, aryl, hydrocarbon, receptor, ligand, endogenous, AHR, ligands, tryptophan-2,3-dioxygenase, TDO, Kyn, Aryl, Hydrocarbon, Receptors, Tryptophan, 2,3, dioxygenase, 4393, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for L-Kynurenine. Do you know of a great paper that uses L-Kynurenine from Tocris? Please let us know.
Average Rating: 5 (Based on 1 Review.)
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I use this product as a standard for Indoleamine 2,3 dioxygenase assay. This product worked excellent as a standard for Tryptophan catabolism assay.
This product is very pure and you can use it from a range of 5 uM to 1500 uM.
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