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Biological Activity for L-Dehydroascorbic acid
L-Dehydroascorbic acid is a oxidized form of L-Ascorbic acid (Cat. No. 4055). Transported into cells through GLUT1. Selectively induces cell death in KRAS and BRAF mutant cells in vitro.
Technical Data for L-Dehydroascorbic acid
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for L-Dehydroascorbic acid
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||1.74||10 with gentle warming|
Preparing Stock Solutions for L-Dehydroascorbic acid
The following data is based on the product molecular weight 174.11. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.74 mL||28.72 mL||57.43 mL|
|5 mM||1.15 mL||5.74 mL||11.49 mL|
|10 mM||0.57 mL||2.87 mL||5.74 mL|
|50 mM||0.11 mL||0.57 mL||1.15 mL|
Product Datasheets for L-Dehydroascorbic acid
References for L-Dehydroascorbic acid
References are publications that support the biological activity of the product.
Kaiser (2015) Vitamin C could target some common cancers. Science 6 6261 PMID: 26542550
Yun et al (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science 11 6266 PMID: 26541605
If you know of a relevant reference for L-Dehydroascorbic acid, please let us know.
Keywords: L-Dehydroascorbic acid, L-Dehydroascorbic acid supplier, vitamin, vit, C, oxidised, form, L-Ascorbic, acid, GLUT1, glucose, transporters, KRAS, BRAF, Glucose, Transporters, Antioxidants, 5734, Tocris Bioscience
Citations for L-Dehydroascorbic acid
Citations are publications that use Tocris products.
Currently there are no citations for L-Dehydroascorbic acid. Do you know of a great paper that uses L-Dehydroascorbic acid from Tocris? Please let us know.
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Literature in this Area
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