Oxidized form of L-Ascorbic acid (Cat. No. 4055). Transported into cells through GLUT1. Selectively induces cell death in KRAS and BRAF mutant cells in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||1.74||10 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 174.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.74 mL||28.72 mL||57.43 mL|
|5 mM||1.15 mL||5.74 mL||11.49 mL|
|10 mM||0.57 mL||2.87 mL||5.74 mL|
|50 mM||0.11 mL||0.57 mL||1.15 mL|
References are publications that support the biological activity of the product.
Kaiser (2015) Vitamin C could target some common cancers. Science 6 6261 PMID: 26542550
Yun et al (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science 11 6266 PMID: 26541605
If you know of a relevant reference for L-Dehydroascorbic acid, please let us know.
Keywords: L-Dehydroascorbic acid, L-Dehydroascorbic acid supplier, vitamin, vit, C, oxidised, form, L-Ascorbic, acid, GLUT1, glucose, transporters, KRAS, BRAF, Glucose, Transporters, Antioxidants, 5734, Tocris Bioscience
Citations for L-Dehydroascorbic acid
Citations are publications that use Tocris products.
Currently there are no citations for L-Dehydroascorbic acid. Do you know of a great paper that uses L-Dehydroascorbic acid from Tocris? Please let us know.
Reviews for L-Dehydroascorbic acid
There are currently no reviews for this product. Be the first to review L-Dehydroascorbic acid and earn rewards!
Have you used L-Dehydroascorbic acid?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.