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Submit ReviewKetotifen fumarate
Description: H1 antagonist
Chemical Name: 4,9-Dihydro-4-(1-methyl-4-piperidinylidene-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
Purity: ≥99% (HPLC)
Biological Activity for Ketotifen fumarate
Ketotifen fumarate is an an H1 receptor antagonist.
Technical Data for Ketotifen fumarate
| M. Wt | 425.5 |
| Formula | C19H19NOS.C4H4O4 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 34580-14-8 |
| PubChem ID | 5282408 |
| InChI Key | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
| Smiles | OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=C1C=CC=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Ketotifen fumarate
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 42.55 | 100 |
Preparing Stock Solutions for Ketotifen fumarate
The following data is based on the product molecular weight 425.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
| 10 mM | 0.24 mL | 1.18 mL | 2.35 mL |
| 50 mM | 0.05 mL | 0.24 mL | 0.47 mL |
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Product Datasheets for Ketotifen fumarate
References for Ketotifen fumarate
References are publications that support the biological activity of the product.
Abu-Dalu et al (1996) The actions of ketotifen on intestinal smooth muscles. Eur.J.Pharmacol. 309 189 PMID: 8874138
Martin and Römer (1978) The pharmacological properties of a new orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene. Arzneimittelforschung 28 770 PMID: 35171
Merck Index 5319
If you know of a relevant reference for Ketotifen fumarate, please let us know.
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Keywords: Ketotifen fumarate, Ketotifen fumarate supplier, H1, antagonists, Receptors, Histamine, histaminergic, 0784, Tocris Bioscience
Citations for Ketotifen fumarate
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