Ketotifen fumarate

Pricing Availability   Qty
Cat.No. 0784 - Ketotifen fumarate | C19H19NOS.C4H4O4 | CAS No. 34580-14-8
Description: H1 antagonist
Chemical Name: 4,9-Dihydro-4-(1-methyl-4-piperidinylidene-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (3)

Biological Activity

An H1 receptor antagonist.

Technical Data

M. Wt 425.5
Formula C19H19NOS.C4H4O4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 34580-14-8
PubChem ID 5282408
InChI Key YNQQEYBLVYAWNX-WLHGVMLRSA-N
Smiles OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.55 100

Preparing Stock Solutions

The following data is based on the product molecular weight 425.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL
10 mM 0.24 mL 1.18 mL 2.35 mL
50 mM 0.05 mL 0.24 mL 0.47 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Abu-Dalu et al (1996) The actions of ketotifen on intestinal smooth muscles. Eur.J.Pharmacol. 309 189 PMID: 8874138

Martin and Römer (1978) The pharmacological properties of a new orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene. Arzneimittelforschung 28 770 PMID: 35171

Merck Index 5319


If you know of a relevant reference for Ketotifen fumarate, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Histamine H1 Receptor Antagonists

Keywords: Ketotifen fumarate, Ketotifen fumarate supplier, H1, antagonists, Receptors, Histamine, histaminergic, 0784, Tocris Bioscience

Citations for Ketotifen fumarate

Citations are publications that use Tocris products.

Currently there are no citations for Ketotifen fumarate. Do you know of a great paper that uses Ketotifen fumarate from Tocris? Please let us know.

Reviews for Ketotifen fumarate

There are currently no reviews for this product. Be the first to review Ketotifen fumarate and earn rewards!

Have you used Ketotifen fumarate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Histamine Receptors

Histamine Receptors Scientific Review

Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.

Asthma

Asthma Poster

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.