Histamine H4 receptor antagonist; displays high affinity (Ki = 4.5 nM) and is >1000-fold selective for H4 over other histamine receptors.
Sold with the permission of Ortho-McNeil-Janssen Pharmaceuticals, Inc.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 277.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.6 mL||18 mL||36 mL|
|5 mM||0.72 mL||3.6 mL||7.2 mL|
|10 mM||0.36 mL||1.8 mL||3.6 mL|
|50 mM||0.07 mL||0.36 mL||0.72 mL|
References are publications that support the products' biological activity.
Jablanowski et al (2003) The first potent and selective non-imidazole human histamine H4 receptor antagonists. J.Med.Chem. 46 3957 PMID: 12954048
Thurmond et al (2004) A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J.Pharmacol.Exp.Ther. 309 404 PMID: 14722321
Strakhova et al (2009) In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. Br.J.Pharmacol. 157 44 PMID: 19413570
If you know of a relevant reference for JNJ 7777120, please let us know.
View Related Products by Product Action
Keywords: JNJ 7777120, supplier, JNJ7777120, histamine, 4, histaminergic, H4, receptors, antagonists, selective, Histamine, H4, Receptors, Histamine, H4, Receptors, Tocris Bioscience
Citations for JNJ 7777120
Citations are publications that use Tocris products.
Currently there are no citations for JNJ 7777120. Do you know of a great paper that uses JNJ 7777120 from Tocris? If so please let us know.
Reviews for JNJ 7777120
There are currently no reviews for this product. Be the first to review JNJ 7777120 and earn rewards!
Have you used JNJ 7777120?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.